Reviewing the Recent Developments in Idiopathic Intracranial Hypertension
Jasvir Virdee, Stephanie J. Larcombe, Vivek Vijay, Alexandra J. Sinclair, Margaret Dayan, Susan P. Mollan
Abstract
There is increasing evidence and appreciation of idiopathic intracranial hypertension (IIH) in medicine. The pathological processes underlying raised intracranial pressure are being studied, with new insights found in both hormonal dysregulation and the metabolic neuroendocrine axis. These will potentially lead to novel therapeutic targets for IIH. The first consensus guidelines have been published on the investigation and management of adult IIH, and the International Headache Society criteria for headache attributable to IIH have been modified to reflect our evolving understanding of IIH. Randomized clinical trials have been published, and a number of studies in this disease area are ongoing.