Changes in bone mineral density after bariatric surgery in patients of different ages or patients with different postoperative periods: a systematic review and meta-analysis
Xiaodan Ou, Mingguang Chen, Lizhen Xu, Wei Lin, Hui‐Bin Huang, Gang Chen, Junping Wen
Abstract
Abstract To assess changes in bone mineral density (BMD) following bariatric surgery (BS) in patients with different bone sites, postoperative periods and ages. Twenty-two studies were included. Femoral neck (FN) BMD decreased after surgery (MD, − 0.05 g/cm 2 , CI − 0.10 to − 0.01, P = 0.03). Postoperative BMD decreased more in the FN and lumbar spine (LS) of patients older than 40 (FNBMD, − 0.07 g/cm 2 , CI − 0.13 to − 0.00, P = 0.04; LSBMD, − 0.03 g/cm 2 , CI − 0.05 to − 0.00, P = 0.02) or patients with a postoperative time of greater than 12 months (FNBMD, − 0.06 g/cm 2 , CI − 0.12 to − 0.01, P = 0.03; LSMD, − 0.04 g/cm 2 , CI − 0.09 to 0.01, P = 0.12); therefore, post-BS bone loss should be monitored among patients in these groups. Longer follow-ups are needed to determine whether BMD changes or stabilizes.