Glutathione-S-transferases genes-promising predictors of hepatic dysfunction
V. P. Prysyazhnyuk, Larysa Sydorchuk, Ruslan Sydorchuk, Iryna Prysiazhniuk, K. O. Bobkovych, І. Buzdugan, Valentina Dzuryak, Petro Prysyazhnyuk
Abstract
genes is involved in the pathogenesis of various liver diseases, particularly non-alcoholic fatty liver disease, hepatitis and liver cirrhosis of different etiology and hepatocellular carcinoma. Certain GST allelic variants were proven to be associated with susceptibility to hepatological pathology, and correlations with the natural course of the diseases were subsequently postulated.
Topics & Concepts
MedicineGlutathioneGeneLiver dysfunctionInternal medicineBioinformaticsEnzymeGeneticsBiochemistryBiologyChemistryGlutathione Transferases and PolymorphismsGenomics, phytochemicals, and oxidative stressFamily Support in Illness