The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study
Isabelle F. Foote, Benjamin M. Jacobs, Georgina Mathlin, Cameron Watson, Phazha LK Bothongo, Sheena Waters, Ruth Dobson, Alastair J. Noyce, Kamaldeep Bhui, Ania Korszun, Charles R. Marshall
Topics & Concepts
PleiotropyGenetic architectureDiseaseStructural equation modelingDementiaRisk factorBiologyAlzheimer's diseaseGenome-wide association studyGenetic associationComputational biologyGeneticsEvolutionary biologyPsychologyBioinformaticsGeneMedicineSingle-nucleotide polymorphismComputer scienceQuantitative trait locusPhenotypeGenotypeMachine learningInternal medicineGenetic Associations and EpidemiologyBioinformatics and Genomic NetworksEpigenetics and DNA Methylation