Novel benzenesulfonamide derivatives linked to diaryl pyrazole tail as potential carbonic anhydrase II/VII inhibitors with anti-epileptic activity
Wael A. A. Fadaly, Mohamed T. M. Nemr, Abeer M. Abd El-Hameed, Simone Giovannuzzi, Mahmoud Abdelrahman Alkabbani, Mohamed M Hefina, Alessio Nocentini, Mamdouh F. A. Mohamed, Claudiu T. Supuran, Wagdy M. Eldehna, Taha H. Zidan
Topics & Concepts
ChemistryCarbonic anhydraseSulfonamidePyrazoleEnzyme inhibitorPharmacologyStereochemistryEnzymeBiochemistryMedicineEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities