Therapeutic synthetic anion transporters
Elba Feo, Philip A. Gale
Abstract
This short review highlights recent examples of small-molecule anion transporters reported in the literature that have potentially useful biological activity. This includes anionophores with antibiotic or antifungal activity, anticancer activity, or the potential to treat channelopathies such as cystic fibrosis. Additionally selective and targeted anion transporters are also discussed.
Topics & Concepts
TransporterComputational biologyChemistryBiologyBiochemistryGeneAmino Acid Enzymes and MetabolismMolecular Sensors and Ion DetectionDrug Transport and Resistance Mechanisms