CRISPR/Cas9-medaited knockout of endogenous T-cell receptor in Jurkat cells and generation of NY-ESO-1-specific T cells: An in vitro study
Pouya Safarzadeh Kozani, Mohammad Ali Shokrgozar, Mehdi Evazalipour, Mehryar Habibi Roudkenar
Topics & Concepts
Jurkat cellsT-cell receptorBiologyT cellMajor histocompatibility complexCell biologyMolecular biologyAntigenAdoptive cell transferImmunologyImmune systemCAR-T cell therapy researchCRISPR and Genetic EngineeringT-cell and B-cell Immunology