Two septal-entorhinal GABAergic projections differentially control coding properties of spatially tuned neurons in the medial entorhinal cortex
Magdalene I. Schlesiger, Tobias Ruff, Duncan A. A. MacLaren, Isabel Barriuso-Ortega, Khalid Magomedovich Saidov, Ting-Yun Yen, Hannah Monyer
Abstract
neurons differentially affects context, reference, and working memory. Together, our results reveal how specific connectivity of septal GABAergic projections with MEC interneurons translates into differential modulation of MEC neuronal coding.
Topics & Concepts
NeuroscienceGABAergicEntorhinal cortexParvalbuminBiologyStimulationPremovement neuronal activityHippocampal formationInhibitory postsynaptic potentialMemory and Neural MechanismsNeuroscience and Neuropharmacology ResearchNeuroendocrine regulation and behavior