Visible-Light Photoredox-Catalyzed Amidation of Benzylic Alcohols
Silvia Gaspa, Andrea Farina, Mariella Tilocca, Andrea Porcheddu, Luisa Pisano, Massimo Carraro, Ugo Azzena, Lidia De Luca
Abstract
A new photocatalyzed route to amides from alcohols and amines mediated by visible light is presented. The reaction is carried out in ethyl acetate as a solvent. Ethyl acetate can be defined a green and bio-based solvent. The starting materials such as the energy source are easily available, stable, and inexpensive. The reaction has shown to be general and high yielding.
Topics & Concepts
ChemistryCatalysisPhotoredox catalysisSolventVisible spectrumEthyl acetateOrganic chemistryKetoneCombinatorial chemistryPhotochemistryPhotocatalysisPhysicsOptoelectronicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsChemical Synthesis and Reactions