<b>Selective Pd-Catalyzed Monoarylation of Small Primary Alkyl Amines through Backbone-Modification in Ylide-Functionalized Phosphines (YPhos)</b>
Ilja Rodstein, Daniel Sowa Prendes, Leon Wickert, Maurice Paaßen, Viktoria H. Gessner
Abstract
could be coupled at room temperature with a series of aryl chlorides in high yields.
Topics & Concepts
ChemistryYlideSteric effectsSubstituentArylAlkylCatalysisLigand (biochemistry)Medicinal chemistryCoupling reactionStereochemistryOrganic chemistryReceptorBiochemistryCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and Catalysis