Pyroptosis inhibitors MCC950 and VX-765 mitigate myocardial injury by alleviating oxidative stress, inflammation, and apoptosis in acute myocardial hypoxia
Xing Ye, Zi-jie Lin, Guang-hui Hong, Zhimin Wang, Run-ting Dou, Junyi Lin, Jianhui Xie, Yiwen Shen
Topics & Concepts
PyroptosisInflammasomeHypoxia (environmental)InflammationApoptosisBiologyMyocardial infarctionOxidative stressProgrammed cell deathBlotCreatine kinaseImmunologyPharmacologyMedicineInternal medicineEndocrinologyChemistryBiochemistryOrganic chemistryGeneOxygenInflammasome and immune disordersGout, Hyperuricemia, Uric AcidPulmonary Hypertension Research and Treatments