The dynamic world of the 8–17 DNAzyme
Jessica Felice Schmuck, Jan Borggräfe, Manuel Etzkorn
Abstract
DNA catalysts, known as DNAzymes, have arguably been limited for decades by the lack of mechanistic information. The solution structure of the 8–17 DNAzyme reported by Wieruszekska, Pwlowicz et al. reassesses the current thinking regarding the relationship between structure, dynamic, and metal ion coordination.
Topics & Concepts
DeoxyribozymeComputational biologyDNANanotechnologyData scienceComputer scienceChemistryGeneticsBiologyMaterials scienceAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry