Imbalance and dizziness caused by unilateral vestibular schwannomas correlate with vestibulo-ocular reflex precision and bias
Susan King, Kilian Dahlem, Faisal Karmali, Konstantina M. Stanković, D. Bradley Welling, Richard F. Lewis
Abstract
The severity of symptoms associated with unilateral vestibular schwannomas (VS) is poorly correlated with standard yaw-axis vestibulo-ocular reflex (VOR) metrics that are based on response amplitude. In this study, we show that the balance and perceptual dysfunction experienced by patients with VS scales with VOR metrics that capture information about the central signal-to-noise ratio (balance) and central static tone (dizziness), but are not correlated with the VOR gain, which reflects central signal amplitude.
Topics & Concepts
Vestibulo–ocular reflexVestibular systemReflexAudiologyVestibular nervePsychologyVestibuleMedicineNeurosciencePhysical medicine and rehabilitationVestibular and auditory disordersOphthalmology and Eye DisordersCerebral Venous Sinus Thrombosis