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Mukaiyama aldol reaction catalyzed by (benz)imidazolium-based halogen bond donors

Revannath L. Sutar, Nikita Erochok, Stefan M. Huber

2021Organic & Biomolecular Chemistry16 citationsDOI

Abstract

or OTf salts were either inactive or showed background reaction through Lewis base catalysis. Repetition experiments clearly ruled out a potential hidden catalysis by elemental iodine and demonstrated the stability of our catalyst over three consecutive cycles.

Topics & Concepts

Aldol reactionCatalysisHalogenChemistryHalogen bondDenticityMedicinal chemistryPolymer chemistryOrganic chemistryCrystal structureAlkylAsymmetric Synthesis and CatalysisAlkaloids: synthesis and pharmacologyIonic liquids properties and applications
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