<i>Salmonella</i>Paratyphi A Outer Membrane Vesicles Displaying Vi Polysaccharide as a Multivalent Vaccine against Enteric Fever
Gianmarco Gasperini, Renzo Alfini, Vanessa Arato, Francesca Mancini, Maria Grazia Aruta, Panchali Kanvatirth, Derek Pickard, Francesca Necchi, Allan Saul, Omar Rossi, Francesca Micoli, Pietro Mastroeni
Abstract
Typhoid and paratyphoid fevers have a high incidence worldwide and coexist in many geographical areas, especially in low-middle-income countries (LMIC) in South and Southeast Asia. There is extensive consensus on the urgent need for better and affordable vaccines against systemic Salmonella infections.
Topics & Concepts
Typhoid feverParatyphoid feverSalmonellaSalmonella typhiEnteric feverMicrobiologyVirologyBiologyEnterobacteriaceaeEnteric bacteriaBacterial outer membraneBacteriaEscherichia coliGeneGeneticsBiochemistrySalmonella and Campylobacter epidemiologyViral gastroenteritis research and epidemiologyVibrio bacteria research studies