A new havanensin-type limonoid from Chisocheton macrophyllus
Nurlelasari Nurlelasari, Intan Rahmayanti, Supriatno Salam, Agus Safari, Desi Harneti, Rani Maharani, Ace Tatang Hidayat, Mulyadi Tanjung, Rurini Retnowati, Yoshihito Shiono, Unang Supratman
Abstract
Abstract A new havanensin-type limonoid, 16β-hydroxydysobinin ( 1 ), along with four known limonoids ( 2–5 ), have been isolated from the seeds of Chisocheton macrophyllus . The chemical structure of the new compound was determined by referencing spectroscopic data, and by comparison to those related spectra previously reported. Each compound was evaluated for their cytotoxic effects against Michigan Cancer Foundation-7 (MCF-7) breast cancer cells and display no significant activity.
Topics & Concepts
LimonoidChemistryStereochemistryPhytochemical compounds biological activities