Electrochemical Synthesis of Thienoacene Derivatives: Transition‐Metal‐Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator
Koichi Mitsudo, Ren Matsuo, Toki Yonezawa, Haruka Inoue, Hiroki Mandai, Seiji Suga
Abstract
Abstract The first electrochemical dehydrogenative C−S bond formation leading to thienoacene derivatives is described. Several thienoacene derivatives were synthesized by dehydrogenative C−H/S−H coupling. The addition of n Bu 4 NBr, which catalytically promoted the reaction as a halogen mediator, was essential.
Topics & Concepts
HalogenElectrochemistryTransition metalChemistryCoupling (piping)MediatorMaterials scienceOrganic chemistryPhysical chemistryCatalysisMetallurgyElectrodeMedicineAlkylInternal medicineSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods