Automated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis
Chen‐Guang Liu, Jiaxun Xie, Wen-Bin Wu, Mu Wang, Weihao Chen, Shabana Binte Idres, Jiawei Rong, Lih‐Wen Deng, Saif A. Khan, Jie Wu
Topics & Concepts
Flow chemistrySolid-phase synthesisContinuous flowChemistryComputer scienceCombinatorial chemistryPharmacophoreBiochemical engineeringNanotechnologyEngineeringBiochemistryPeptideMaterials scienceInnovative Microfluidic and Catalytic Techniques InnovationChemical Synthesis and AnalysisChemical synthesis and alkaloids