SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential
Neha Vithani, Michael D. Ward, Maxwell I. Zimmerman, Borna Novak, Jonathan Borowsky, Sukrit Singh, Gregory R. Bowman
Topics & Concepts
CoronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Mechanism (biology)2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirusVirologyBetacoronavirusBiologyMedicinePhysicsInfectious disease (medical specialty)PathologyQuantum mechanicsOutbreakDiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesComputational Drug Discovery Methods