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Advances in SHP2 tunnel allosteric inhibitors and bifunctional molecules

Zhichao Guo, Yiping Duan, Kai Sun, Tiandong Zheng, Jie Liu, Shengtao Xu, Jinyi Xu

2024European Journal of Medicinal Chemistry23 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryAllosteric regulationBifunctionalStereochemistryBiochemistryEnzymeCatalysisProtein Tyrosine PhosphatasesPI3K/AKT/mTOR signaling in cancerPeptidase Inhibition and Analysis
Advances in SHP2 tunnel allosteric inhibitors and bifunctional molecules | Litcius