ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
Matthew B. Maxwell, Marianne S. Hom, Jawoon Yi, Shitian Li, Samuel A. Rivera, Jingting Yu, Mannix J. Burns, Helen M. McRae, Braden T. Stevenson, Katherine Coakley, Josephine Ho, Kameneff Bojorquez Gastelum, Joshua C. Bell, Alexander C. Jones, Ramez N. Eskander, Emily C. Dykhuizen, Gerald S. Shadel, Susan M. Kaech, Diana C. Hargreaves
Topics & Concepts
ARID1ABiologyCancer researchDownregulation and upregulationInterferonStingMicrosatellite instabilityMutantImmune systemMolecular biologyGeneImmunologyMutationGeneticsMicrosatelliteAlleleAerospace engineeringEngineeringChromatin Remodeling and Cancerinterferon and immune responsesCancer Mechanisms and Therapy