Litcius/Paper detail

ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

Matthew B. Maxwell, Marianne S. Hom, Jawoon Yi, Shitian Li, Samuel A. Rivera, Jingting Yu, Mannix J. Burns, Helen M. McRae, Braden T. Stevenson, Katherine Coakley, Josephine Ho, Kameneff Bojorquez Gastelum, Joshua C. Bell, Alexander C. Jones, Ramez N. Eskander, Emily C. Dykhuizen, Gerald S. Shadel, Susan M. Kaech, Diana C. Hargreaves

2024Cell113 citationsDOIOpen Access PDF

Topics & Concepts

ARID1ABiologyCancer researchDownregulation and upregulationInterferonStingMicrosatellite instabilityMutantImmune systemMolecular biologyGeneImmunologyMutationGeneticsMicrosatelliteAlleleAerospace engineeringEngineeringChromatin Remodeling and Cancerinterferon and immune responsesCancer Mechanisms and Therapy