The myonuclear DNA methylome in response to an acute hypertrophic stimulus
Ferdinand von Walden, Matthew Rea, C. Brooks Mobley, Yvonne Fondufe‐Mittendorf, John J. McCarthy, Charlotte A. Peterson, Kevin A. Murach
Abstract
using RRBS, and demonstrates the importance of isolating specific nuclear populations to study the epigenetic regulation of skeletal muscle fibre adaptation.
Topics & Concepts
BiologySkeletal muscleDNA methylationCell biologyEpigeneticsTSC1RHEBMolecular biologyPI3K/AKT/mTOR pathwayGeneticsmTORC1Gene expressionGeneAnatomySignal transductionEpigenetics and DNA MethylationGenetics and Neurodevelopmental DisordersMuscle Physiology and Disorders