In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH
Sean K. Wang, Sylvain W. Lapan, Christin M. Hong, Tyler B. Krause, Constance L. Cepko
Abstract
, allowing for studies of AAV vector biology and the tracking of transduced cells following vector administration.
Topics & Concepts
Fish <Actinopterygii>In situBiologyVector (molecular biology)GenomeIn situ hybridizationVirologyComputational biologyPhysicsGeneticsFisheryGeneGene expressionMeteorologyRecombinant DNAVirus-based gene therapy researchCRISPR and Genetic EngineeringAnimal Virus Infections Studies