Characterization and monitoring of charge variants of a recombinant monoclonal antibody using microfluidic capillary electrophoresis-mass spectrometry
Qiang Sun, Liang Wang, Na Li, Liming Shi
Topics & Concepts
DeamidationCapillary electrophoresis–mass spectrometryMonoclonal antibodyChemistryChromatographyMass spectrometryCapillary electrophoresisMicrofluidicsRecombinant DNAElectrophoresisPeptideGel electrophoresisAntibodyBiochemistryElectrospray ionizationEnzymeBiologyNanotechnologyMaterials scienceImmunologyGeneProtein purification and stabilityMicrofluidic and Capillary Electrophoresis ApplicationsMonoclonal and Polyclonal Antibodies Research