Age- and sex-associated differences in immune cell populations
Reza Gheitasi, Sabine Baumgart, Daniela Roell, Norman Rose, Carsten Watzl, Diana Dudziak, Nico Andreas, Oliwia Makarewicz, Sebastian Drube, Clara Schnizer, Thomas Kamradt, Sebastian Weis, Mathias W. Pletz
Abstract
effector memory T cells in men. Additionally, numbers of dendritic cell subpopulations decreased with age in both sexes. This study provides new insights into complex dependencies of the immune cell composition on age and sex (e.g., age × sex interaction effects) and could enhance our understanding of immune status variations among different ages. However, further studies are needed to assess the functional implications of these compositional differences.
Topics & Concepts
Immune systemBiologyPhysiologyImmunologyImmune Cell Function and InteractionSex and Gender in HealthcareT-cell and B-cell Immunology