Development of a covalent inhibitor of gut bacterial bile salt hydrolases
Arijit A. Adhikari, T.C.M. Seegar, Scott B. Ficarro, Megan D. McCurry, Deepti Ramachandran, Lina Yao, Snehal N. Chaudhari, Sula Ndousse-Fetter, Alexander S. Banks, Jarrod A. Marto, Stephen C. Blacklow, A. Sloan Devlin
Topics & Concepts
BiochemistryBile acidChemistryCovalent bondEnzymeGut floraBacteriaBiologyMicrobiologyOrganic chemistryGeneticsDrug Transport and Resistance MechanismsPediatric Hepatobiliary Diseases and TreatmentsHIV/AIDS drug development and treatment