Structural and dynamic studies of TAPBPR and Tapasin reveal the mechanism of peptide loading of MHC-I molecules
David H. Margulies, Jiansheng Jiang, Kannan Natarajan
Topics & Concepts
CalreticulinTransporter associated with antigen processingMHC class IChaperone (clinical)Cell biologyMajor histocompatibility complexEndoplasmic reticulumBiologyCalnexinAntigen processingChemistryBiochemistryGenePathologyMedicineImmune Cell Function and InteractionEndoplasmic Reticulum Stress and DiseaseImmunotherapy and Immune Responses