Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice
Dan Li, Nan Li, Yifan Zhang, Haiying Fu, Mingqian Feng, Dina Schneider, Ling Su, Xiaolin Wu, Jing Zhou, Sean Mackay, Josh Kramer, Zhijian Duan, Hongjia Yang, Aarti Kolluri, Alissa M. Hummer, Madeline B. Torres, Hu Zhu, Matthew D. Hall, Xiaoling Luo, Jinqiu Chen, Qun Wang, Daniel Abate‐Daga, Boro Dropulić, Stephen M. Hewitt, Rimas J. Orentas, Tim F. Greten, Mitchell Ho
Topics & Concepts
Chimeric antigen receptorCancer researchGlypican 3AntigenHepatocellular carcinomaCD34Granzyme BBiologyMolecular biologyChemistryImmunologyImmunotherapyStem cellCell biologyCD8Immune systemCAR-T cell therapy researchImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research