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Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression

Stefano Comai, Elisa Melloni, Cristina Lorenzi, Irene Bollettini, Benedetta Vai, Raffaella Zanardi, Cristina Colombo, Flavia Valtorta, Francesco Benedetti, Sara Poletti

2021European Neuropsychopharmacology57 citationsDOI

Topics & Concepts

KynurenineInternal medicineBipolar disorderKynurenine pathwayEndocrinologyFractional anisotropyCorpus callosumMajor depressive disorderMedicineWhite matterCytokineDepression (economics)TryptophanPsychologyChemistryAmygdalaPathologyBiochemistryMagnetic resonance imagingLithium (medication)EconomicsMacroeconomicsRadiologyAmino acidTryptophan and brain disordersBipolar Disorder and TreatmentStress Responses and Cortisol
Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression | Litcius