Virtual-screening of xanthine oxidase inhibitory peptides: Inhibition mechanisms and prediction of activity using machine-learning
Qian Chen, Yuxi Ge, Xiaoyu He, Shanshan Li, Zhengfeng Fang, Li Cheng, Hong Chen
Topics & Concepts
Virtual screeningXanthine oxidaseInhibitory postsynaptic potentialHyperuricemiaChemistryBiochemistryPeptideQuantitative structure–activity relationshipAmino acidDocking (animal)XanthineUric acidComputational biologyStereochemistryEnzymeBiologyDrug discoveryMedicineNeuroscienceNursingGout, Hyperuricemia, Uric AcidPharmacological Effects of Natural CompoundsHepatitis C virus research