Coexistence of <i>tmexCD-toprJ</i> , <i>bla</i> <sub>NDM-1</sub> , and <i>bla</i> <sub>IMP-4</sub> in One Plasmid Carried by Clinical <i>Klebsiella</i> spp.
Tao Xiao, Kai Peng, Qi Chen, Xueqin Hou, Weifeng Huang, Hong Lv, Xiaorong Yang, Gaopeng Lei, Ruichao Li
Abstract
, hinting that this plasmid could be a critical vector for superbug development. Furthermore, we discovered that the carbapenem and tigecycline resistance genes are located in mobile units by genetic structure analysis. Our research tracks the formation of clinically super-resistant Gram-negative bacteria.
Topics & Concepts
TigecyclineKlebsiella pneumoniaeKlebsiellaPlasmidMicrobiologyKlebsiella infectionsBiologyEnterobacteriaceaeAntibioticsMedicineGeneticsEscherichia coliGeneAntibiotic Resistance in BacteriaTuberculosis Research and EpidemiologyAntibiotics Pharmacokinetics and Efficacy