The Omicron (B.1.1.529) variant of SARS-CoV-2 binds to the hACE2 receptor more strongly and escapes the antibody response: Insights from structural and simulation data
Abbas Khan, Hira Waris, Memoona Rafique, Muhammad Suleman, Anwar Mohammad, Syed Shujait Ali, Taimoor Ashraf Khan, Yasir Waheed, Chenguang Liao, Dong‐Qing Wei
Topics & Concepts
PhenotypeMutantSpike ProteinHydrogen bondSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ChemistryMolecular dynamicsAntibodyComputational biologyGeneticsCoronavirus disease 2019 (COVID-19)BiologyGeneMoleculeMedicineComputational chemistryOrganic chemistryInfectious disease (medical specialty)DiseasePathologySARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies ResearchComputational Drug Discovery Methods