Pathological matrix stiffness promotes cardiac fibroblast differentiation through the POU2F1 signaling pathway
Mingzhe Li, Jimin Wu, Guomin Hu, Yao Song, Jing Shen, Junzhou Xin, Zijian Li, Wei Liu, Erdan Dong, Ming Xu, Youyi Zhang, Han Xiao
Topics & Concepts
Extracellular matrixFibrosisChromatin immunoprecipitationTranscription factorGene knockdownDownregulation and upregulationCell biologyCardiac fibrosisBiologyMyofibroblastCellular differentiationCancer researchRepressorMolecular biologyPromoterChemistryGene expressionGenePathologyMedicineGeneticsCardiac Fibrosis and RemodelingCell Adhesion Molecules ResearchPeptidase Inhibition and Analysis