Evolution in non-peptide α-helix mimetics on the road to effective protein-protein interaction modulators
Sergio Algar, Mercedes Martín‐Martínez, Rosario González‐Muñiz
Topics & Concepts
PeptidomimeticChemistrySmall moleculeHelix (gastropod)InteractomePeptideProtein–protein interactionPharmacophoreDrug discoveryAmino acidSide chainMoleculeCombinatorial chemistryStereochemistryComputational biologyBiochemistryPolymerEcologyOrganic chemistryGeneSnailBiologyChemical Synthesis and AnalysisClick Chemistry and ApplicationsUbiquitin and proteasome pathways