Adjunctive Probiotics Alleviates Asthmatic Symptoms via Modulating the Gut Microbiome and Serum Metabolome
Ailing Liu, Teng Ma, Ning Xu, Hao Jin, Feiyan Zhao, Lai‐Yu Kwok, Heping Zhang, Shukun Zhang, Zhihong Sun
Abstract
The human gut microbiota has a potential effect on the pathogenesis of asthma and is closely related to the disease phenotype. Our trial has demonstrated that co-administering Probio-M8 synergized with conventional therapy to alleviate asthma symptoms. The findings of the present study provide new insights into the pathogenesis and treatment of asthma, mechanisms of novel therapeutic strategies, and application of probiotics-based therapy.
Topics & Concepts
Bifidobacterium animalisProbioticExhaled nitric oxidePlaceboAsthmaMedicineDysbiosisInternal medicineBifidobacteriumGastroenterologyImmunologyGut floraLactobacillusBiologySpirometryFood sciencePathologyBacteriaAlternative medicineFermentationGeneticsGut microbiota and healthProbiotics and Fermented FoodsAsthma and respiratory diseases