Reduced FNDC5-AMPK signaling in diabetic atrium increases the susceptibility of atrial fibrillation by impairing mitochondrial dynamics and activating NLRP3 inflammasome
Shan Meng, Xin Chen, Jikai Zhao, Xinyi Huang, Yuting Huang, Tao Huang, Zijun Zhou, Wenpu Ren, Tao Hong, Jinfeng Duan, Liming Yu, Huishan Wang
Topics & Concepts
InflammasomeAMPKAtrial fibrillationInternal medicineMedicineFibrillationCardiologyAtrium (architecture)ChemistryEndocrinologyBiologyCell biologyReceptorProtein kinase APhosphorylationCardiovascular Function and Risk FactorsEndoplasmic Reticulum Stress and DiseaseMitochondrial Function and Pathology