Litcius/Paper detail

Transition-metal-catalyzed reactions involving reductive elimination between dative ligands and covalent ligands

Tianxiao Jiang, Haocheng Zhang, Yongzheng Ding, Suchen Zou, Rui Chang, Hanmin Huang

2020Chemical Society Reviews55 citationsDOI

Abstract

Reductive elimination is a crucial bond-forming elementary reaction in various transition-metal mediated reactions. Apart from the well-developed classic reductive elimination, the non-classic reductive elimination occurring between a covalent ligand and a dative ligand, which has been known for over 50 years, has gradually attracted much attention from the organic community. By avoiding pπ-dπ repulsion between the filled metal d-orbital and the filled ligand p-orbital and forming a cationic-type molecule, non-classic reductive elimination could facilitate many catalytic reactions that were difficult to be realized via classic reductive elimination. In this review, transition-metal catalyzed C-P, C-S, C-N, and C-C bond-forming reactions with non-classic reductive elimination as the key elementary step are summarized.

Topics & Concepts

CatalysisDative caseChemistryTransition metalCovalent bondCombinatorial chemistryReductive eliminationMetalOrganic chemistryPhilosophyLinguisticsCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisCyclopropane Reaction Mechanisms