Litcius/Paper detail

Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells

Khrystyna North, Salima Benbarche, Bo Liu, Joseph Pangallo, Sisi Chen, Maximilian Stahl, Jan Philipp Bewersdorf, Robert Stanley, Caroline Erickson, Hana Cho, Jose Mario Bello Pineda, James D. Thomas, Jacob T. Polaski, Andrea E. Belleville, Austin M. Gabel, Dylan B. Udy, Olivier Humbert, Hans‐Peter Kiem, Omar Abdel‐Wahab, Robert K. Bradley

2022Nature Biotechnology63 citationsDOIOpen Access PDF

Topics & Concepts

RNA splicingIntronBiologySplicing factorMutationCancer cellCancer researchGeneCancerMolecular biologyRNAGeneticsVirus-based gene therapy researchRNA Interference and Gene DeliveryRNA Research and Splicing