A Comparative Genomic Approach to Determine the Virulence Factors and Horizontal Gene Transfer Events of Clinical Acanthamoeba Isolates
Xiaobin Gu, Xiuhai Lu, Shudan Lin, Xinrui Shi, Yue Shen, Qingsong Lu, Yiying Yang, Jing Yang, Jiabei Cai, Chunyan Fu, Yongliang Lou, Meiqin Zheng
Abstract
Acanthamoeba has the ability to cause serious blinding keratitis. Although the prevalence of this phenomenon has increased in recent years, our knowledge of the underlying opportunistic pathogenic mechanism maybe remains incomplete.
Topics & Concepts
AcanthamoebaBiologyHorizontal gene transferVirulenceGeneticsPhylogenetic treeGeneComparative genomicsPhylogeneticsGenomeMicrobiologyGenomicsLegionella and Acanthamoeba researchBacillus and Francisella bacterial researchVibrio bacteria research studies