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Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA

Fanny Joubert, Michael J. Munson, Alan Sabirsh, R. England, Martin Hemmerling, Cameron Alexander, Marianne Ashford

2023Journal of Controlled Release55 citationsDOI

Topics & Concepts

DendrimerChemistryLysineMessenger RNAEndosomeGene deliveryTransfectionBiophysicsTranslation (biology)CellNanotechnologyCombinatorial chemistryBiochemistryAmino acidMaterials scienceBiologyGeneRNA Interference and Gene DeliveryDendrimers and Hyperbranched PolymersAdvanced biosensing and bioanalysis techniques
Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA | Litcius