Antibacterial Cascade Catalytic Glutathione-Depleting MOF Nanoreactors
Xi Zhou, Shuai Zhang, Yan Liu, Jiashen Meng, M. Wang, Yaoji Sun, Linbo Xia, Zhaozhi He, Wenxin Hu, Lei Ren, Zhiwei Chen, Xingcai Zhang
Abstract
and produces a large amount of toxic reactive oxygen species. In addition, MMAG consumed GSH, which can result in bacterial death more easily. Systematic antibacterial experiments illustrated that MMAG has superior antibacterial effects on both Gram-positive bacteria and Gram-negative bacteria.
Topics & Concepts
GlutathioneAntibacterial activityNanoreactorBacteriaReactive oxygen speciesCatalysisPathogenic bacteriaAntibioticsMicrobiologyMaterials scienceCombinatorial chemistryChemistryBiologyBiochemistryEnzymeGeneticsAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranosticsNanocluster Synthesis and Applications