Interfacing non-enzymatic catalysis with living microorganisms
Joanna C. Sadler, Jonathan A. Dennis, Nick Johnson, Stephen Wallace
Abstract
Interfacing non-enzymatic catalysis with cellular metabolism is emerging as a powerful approach to produce a range of high value small molecules and polymers. In this review, we highlight recent examples from this promising young field. Specifically, we discuss demonstrations of living cells mediating redox processes for biopolymer production, interfacing solar-light driven chemistry with microbial metabolism, and intra- and extracellular non-enzymatic catalysis to generate high value molecules. This review highlights the vast potential of this nascent field to bridge the two disciplines of synthetic chemistry and synthetic biology for a sustainable chemical industry.
Topics & Concepts
InterfacingNanotechnologyBiochemical engineeringBiopolymerChemistrySynthetic biologyMaterials scienceComputer sciencePolymerBiologyComputational biologyOrganic chemistryEngineeringComputer hardwareInnovative Microfluidic and Catalytic Techniques InnovationEnzyme Catalysis and ImmobilizationElectrochemical sensors and biosensors