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Highly Doped Upconversion Nanoparticles for <i>In Vivo</i> Applications Under Mild Excitation Power

Du Li, Shihui Wen, Mengya Kong, Yongtao Liu, Wei Hu, Bingyang Shi, Xiangyang Shi, Dayong Jin

2020Analytical Chemistry28 citationsDOIOpen Access PDF

Abstract

, bringing down the excitation power requirement by 42 times. This work redefines the doping concentrations to fight for the issue of concentration quenching, so that ultrasmall and bright nanoparticles can be used to further improve the performance of upconversion nanotechnology in photodynamic therapy, light-triggered drug release, optogenetics, and night vision enhancement.

Topics & Concepts

Photon upconversionExcitationBrightnessDopingChemistryIn vivoNanoparticleIonActivator (genetics)FluorescenceNanotechnologyOptoelectronicsOpticsMaterials sciencePhysicsOrganic chemistryBiotechnologyBiochemistryQuantum mechanicsBiologyGeneLuminescence Properties of Advanced MaterialsRadiation Detection and Scintillator TechnologiesLuminescence and Fluorescent Materials