Nickel‐asparagine complex fixed on a magnetic substrate as a precursor for preparing substituted acridines
Maryam Abbaszadehghan, Ahmad Poursattar Marjani, Sepideh Bibak, Hamideh Sarreshtehdar Aslaheh
Abstract
In this work, an efficient, novel, retrievable, and magnetic heterogeneous nanocatalyst, Fe 3 O 4 @CPTMS@Asp@Ni was successfully fabricated using Fe 3 O 4 nanoparticles as the core that were coated with surfactant and 3‐chloropropyltrimethoxysilan and deposited asparagine and nickel metal that can be used in multicomponent reactions for the synthesis of acridines derivatives with high yield in short reaction times. The virtue of obtained nanocatalyst was identified using transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X‐ray diffraction analysis, energy dispersive X‐ray, Brunauer–Emmett–Teller, vibrating sample magnetometry, Raman, and thermogravimetric analysis. The X‐ray diffraction analysis studies demonstrate that the average crystallite sizes of the prepared nanocatalyst are estimated to be about 45.4 nm. Also, the vibrating sample magnetometry measurement shows saturation magnetization values (Ms) of 7 emu/g for Fe 3 O 4 @CPTMS@Asp@Ni nanocatalyst. Also, after the synthesis steps, the application of the prepared nanocatalyst in the preparation of acridine‐1,8(2 H ,5 H )‐diones has been investigated. Then to evaluate and assess the efficiency of the nanocatalyst as mentioned above, and its effect on the synthesis of divergent acridines via a one‐pot, three‐component condensation reaction of cyclic 1,3‐dione, aryl glyoxal, with ammonium acetate in the water as green solvent was studied. Also, when investigating the reusability of this catalyst, it was observed that Fe 3 O 4 @CPTMS@Asp@Ni nanocatalyst could be reused at least five times without losing its efficiency. High efficiency, outstanding yields in quick intervals, easy separation using a magnetic field, and possessing reusability are significant benefits of the attained nanocatalyst.