Litcius/Paper detail

Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress

Ram Sharma, Yung‐Hsiao Chiang, Hsien-Chung Chen, Hong‐Yi Lin, Wen‐Bin Yang, Kunal Nepali, Mei-Jung Lai, Kai‐Yun Chen, Jing‐Ping Liou, Tsung‐I Hsu

2024Cancer Letters20 citationsDOI

Topics & Concepts

TemozolomideOxidative stressCYP17A1Cancer researchDNA damagePharmacologyApoptosisIn vivoMedicineChemistryBiologyInternal medicineGlioblastomaDNABiochemistryGeneBiotechnologyHistone Deacetylase Inhibitors ResearchGlioma Diagnosis and TreatmentBrain Metastases and Treatment