Iron transport mechanism of lactoferrin and its application in food processing
Jianing Fu, Yang Liu, Dehong TAN, Ling Liu
Abstract
Lactoferrin (LF) is a non-heme protein binding Fe3+ tightly and plays a role in regulating the absorption and metabolism of iron under physiological condition. The absorption of non-heme iron occurs in the duodenum. LF is incorporated as a functional factor of food products during food processing. In this review, we describe the structural and functional changes of LF due to thermal processing of food, as well as the metabolic processes of LF iron binding and release in vivo, which characterizes the value of LF as a food matrix from nutrition and biochemistry and provides a basis for the comprehensive utilization of LF in food.
Topics & Concepts
LactoferrinHemeChemistryBiochemistryMechanism (biology)Food scienceDuodenumBiophysicsBiologyEnzymeInternal medicineMedicinePhilosophyEpistemologyInfant Nutrition and HealthIron Metabolism and DisordersClinical Nutrition and Gastroenterology