Cation–π and hydrophobic interaction controlled PET recognition in double mutated cutinase – identification of a novel binding subsite for better catalytic activity
Anjima James, Susmita De
Abstract
) found in the newly discovered subsite, but also favours the fully extended PET conformation. This subsequently impacts the overall increased catalytic activity of mutated cutinase.
Topics & Concepts
CutinaseAlanineChemistryStereochemistryResidue (chemistry)Alanine scanningHydrolysisAmino acidMutationBiochemistryMutagenesisGeneMicroplastics and Plastic PollutionEffects and risks of endocrine disrupting chemicalsPolymer crystallization and properties