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The once and future gene therapy

Karen Bulaklak, Charles A. Gersbach

2020Nature Communications322 citationsDOIOpen Access PDF

Abstract

Gene therapy is at an inflection point. Recent successes in genetic medicine have paved the path for a broader second wave of therapies and laid the foundation for next-generation technologies. This comment summarizes recent advances and expectations for the near future.

Topics & Concepts

Genetic enhancementInflection pointFoundation (evidence)Computer scienceMedicineBioinformaticsComputational biologyEngineering ethicsIntensive care medicineBiologyGeneGeneticsPolitical scienceEngineeringLawMathematicsGeometryCRISPR and Genetic EngineeringVirus-based gene therapy researchCAR-T cell therapy research
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