Esophageal wall compliance/stiffness during peristalsis in patients with functional dysphagia and high-amplitude esophageal contractions
Ali Zifan, Vignesh Gandu, Ravinder K. Mittal
2022American Journal of Physiology-Gastrointestinal and Liver Physiology10 citationsDOIOpen Access PDF
Abstract
We studied healthy asymptomatic subject, patients with functional dysphagia (FD), and patients with high-amplitude esophageal contractions (HAEC). Our data show that in patients with HAEC and functional dysphagia, luminal distension is smaller (low luminal CSA at peak distension), intraluminal pressure is higher, and liquid bolus travels faster through the esophagus as compared with normal subjects. We conclude that patients with functional dysphagia and HAEC have a stiffer distal esophageal wall during bolus transport related to primary peristalsis.
Topics & Concepts
PeristalsisDistensionDysphagiaEsophagusMedicineBolus (digestion)SwallowingAchalasiaEsophageal motility disorderInternal medicineCardiologySurgeryGastroesophageal reflux and treatmentsDysphagia Assessment and ManagementEsophageal and GI Pathology