FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development
James M. Byrne, Ursula Waack, Edward A. Weinstein, Abhay Joshi, Simone M. Shurland, Dmitri Iarikov, Jürgen B. Bulitta, Binh An Diep, Tína Guina, William Hope, Matthew B. Lawrenz, Alexander J. Lepak, Brian Luna, Lynn Miesel, Andrew J. Phipps, Thomas J. Walsh, Jason Weiss, Thushi Amini, John Farley
Abstract
The U.S. Food and Drug Administration (FDA) hosted a public workshop entitled “Advancing Animal Models for Antibacterial Drug Development” on 5 March 2020. The workshop mainly focused on models of pneumonia caused by Pseudomonas aeruginosa and Acinetobacter baumannii . The program included discussions from academic investigators, industry, and U.S. government scientists. The potential use of mouse, rabbit, and pig models for antibacterial drug development was presented and discussed.